Plot hole: In the scene where Bart has to choose the right Roman numeral door in order to avoid the tigers; right as the Shelbyville kids come bursting through the outer door, Bart picks the right door through humorous deduction and escapes. However, the Shelbyville kids are unable to open the door which doesn't make sense, since there is no lock on the door and there wasn't any mention of Bart blocking or sabotaging the door because only a few seconds later we see him on the street continuing to fret about the lemon tree.
So It Has Come to This: The Simpsons Clip Show - S4-E18
Audio problem: After Homer puts the old milk in the fridge and Bart takes a drink from it you will then see Marge use a fork to take the milk out of the carton. Marge says "woof" but her mouth does not move in sequence with the audio.
Scuse Me While I Miss the Sky - S14-E16
Continuity mistake: When Skinner opens the door to the room Lisa is in, there is a red book with white rings around it behind the door, it is easily the most noticeable book on the shelf. When the shot cuts back, the book is suddenly blue.
Continuity mistake: At the end of the episode in church when the group of parishioners moves forward to forgive Ned there is a woman amongst the group who has light green hair. However, when there is a wide angle shot of the group again she is nowhere to be seen.
Continuity mistake: When Homer starts walking away with the stone of shame, you can see he has no birth mark on him. yet in the next shot all off the stonecutters see the birthmark.
Continuity mistake: Right at the very end scene, when Lisa and Maggie are sitting on the bed, you can see that there are 6 bricks on the bed. Yet when the shot changes there is only one behind Maggie, meaning two of them have just vanished. (00:20:30)
Much Apu About Nothing - S7-E23
Continuity mistake: When Bart pulls out Apu's punch cards, there are many sitting on top of the box. When Apu picks the box up and places it in the bin, there are only a few cards sitting on top.
The Ziff Who Came to Dinner - S15-E14
Continuity mistake: In once scene, Artie walks past the Simpson's to Selma (or Patty). In the next shot he is shown walking past the Simpson's again.
Alone Again Natura-Diddly - S11-E14
Continuity mistake: In the episode where Maude dies, Homer puts Ned to bed in the right hand side. When Ned tells Rachel he's ready to smooth out Maude's shape, they smooth out the right hand side.
Continuity mistake: In the scene where Bart and Homer find Marge's paintings in the attic, there is a shot of the paintings all stacked up and you can see that the edges of all of them are the same shade of pink as The Front painting. However, when the boys flick through the paintings, the backgrounds and edges are a variety of colours, including pale blue.
Bart Gets Hit By a Car - S2-E10
Other mistake: When Marge is being questioned, before she says 'If you don't have anything nice to say, then don't say anything at all', there is a shot over her shoulder looking at the blue haired lawyer. Not only is he (the lawyer) there directly in front of her, but he is also sitting on the bench with Burns. In all other shots his chair is empty as it should be.
Like Father, Like Klown - S3-E6
Continuity mistake: During Krusty's performance, the tables change from round to long and rectangular. (00:09:10 - 00:10:10)
Audio problem: After Barney falls over in his chair, you can hear him say, "Hmm, a pretzel." His mouth doesn't move. (00:21:15)
Continuity mistake: At the end of the episode, when we see a wide shot of everyone going to join Ned on the hill (and singing the song) look to the far left. You will see Apu - and his skin is yellow.
There's No Disgrace Like Home - S1-E4
Continuity mistake: When the Simpsons are spying on the old man, the boy and the old woman, all three of them disappear and then reappear between shots. Whenever there is a wide shot from outside the house, they are not there but when there is a close shot from outside or inside they are there. (00:11:00)
And Maggie Makes Three - S6-E13
Continuity mistake: When Homer is trying to get Ned another woman in a different episode, he tells him that there was some footage of Maggie being born that he couldn't get rid of on the tape but in the scene (in this episode)when Maggie is being born there are no video cameras in sight.
Continuity mistake: When the family is at dinner, there is a top down view which zooms in on them from above. In this shot there is no newspaper on the chest (to Homer's left). In the next shot of Homer a newspaper has appeared. (00:07:50)
A Streetcar Named Marge - S4-E2
Continuity mistake: As Marge is about to leave for her first audition, she walks across the room and she is wearing white slip-on shoes. Then her and Homer talk for a bit, then when it cuts to a wider shot after they talk, she now has her red flat-heels on. (00:03:30 - 00:04:00)
Mr. Lisa Goes to Washington - S3-E2
Plot hole: The Simpsons take a flight to Washington D.C. for Lisa's speech. But it is revealed in a later episode that Marge has a Fear of Flying. This was before it was discovered that she had a Fear of Flying.
Homer's Barbershop Quartet - S5-E1
Audio problem: When Homer is playing on the piano, he says the word "fault". When he says this you can hear a key being pressed but Homer doesn't touch any keys.
Answer: I'm not sure if this is the one you're thinking of, but an episode of "Ray Bradbury Theatre," called "A Sound of Thunder," dealt with a similar matter: a group of hunters travel back in time to hunt dinosaurs, only to find things have changed when they get back because someone stepped on a butterfly.
Xofer