Blade II (2002) ending / spoiler
It turns out Nomak is Nyssa's brother, the Reapers are a new breed of vampires (not a new virus), Scud doublecrosses Blade (he is working for Nyssa's father). Nomak kills Nyssa's father. Blade kills Reinhart and Nomak; Scud, of course, pays for his treachery. Nyssa is mortally wounded and dies watching her first sunrise.