Trivia: Lee Majors and Heather Thomas, who portrayed Colt Seavers and Jody Banks in the original television series, have cameos as the police officers who arrest Gail and Tom during the mid-credit scene.
Trivia: This film will actually have the shortest amount of time elapsed between installments, releasing around 2 years and 4 months after Ghostbusters: Afterlife. Ghostbusters 2 released 5 years after the original film, the 2016 film released 27 years after Ghostbusters 2, and Ghostbusters: Afterlife released 5 years after the 2016 film.
Trivia: Chip, who plays the role of Alfie (Ellie's cat), is the pet cat of Claudia Schiffer, the wife of the film's director, Matthew Vaughn.
Trivia: The restaurant near the bookstore where Charlie works is called the Double Deuce. Double Deuce was the name of the Road House in the 1989 film version.
Trivia: This is the first MCU film since 2008's The Incredible Hulk to feature Liv Tyler as Betty Ross and Tim Blake Nelson as Samuel Sterns a.k.a. The Leader. They were the last two of that film's five main characters to reappear in the franchise.
Trivia: Michael Keaton said at Cinemacon 2024 that this was the most fun he ever had making a film.